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Mortality among people with OCD.

Several mental disorders have consistently been found to be associated with decreased life expectancy, but little is known about whether this is also the case for obsessive-compulsive disorder (OCD). The aim of a new research published in JAMA Psychiatry was to determine whether people who receive a diagnosis of OCD are at increased risk of death. The experts conducted a nationwide prospective cohort study with 30 million person-years of follow-up, using data from Danish longitudinal registers. It has been estimated mortality rate ratios (MRRs), adjusted for calendar year, age, sex, maternal and paternal age, place of residence at birth and somatic comorbidities, to compare people with OCD with the ones without OCD. Of 10.155 people suffering with that disorder, 110 (1.1%) died during the average follow-up of 9.7 years. The risk of death by natural or unnatural causes was significantly higher among individuals with OCD than among the general population. Moreover, after the exclusion of people with comorbid anxiety disorders, depression or substance use disorders, OCD was still associated with increased mortality risk.